IN SITU TRANSPLANTATION OF ADIPOSE-DERIVED STEM CELLS VIA PHOTOACTIVATION IMPROVES GLUCOSE METABOLISM IN OBESE MICE

In situ transplantation of adipose-derived stem cells via photoactivation improves glucose metabolism in obese mice

Abstract Background Accumulating evidence suggests that enhanced adipose tissue macrophages (ATMs) are associated with metabolic disorders in obesity and type 2 diabetes.However, therapeutic persistence and reduced homing stem cell function following cell delivery remains a critical hurdle for the clinical translation of stem cells in current appro

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Zymobacter palmae Pyruvate Decarboxylase is Less Effective Than That of Zymomonas mobilis for Ethanol Production in Metabolically Engineered Synechocystis sp. PCC6803

To produce bioethanol from model cyanobacteria such as Synechocystis, a two gene cassette consisting of genes encoding pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) are required to transform pyruvate first to acetaldehyde and then to ethanol.However the partition of pyruvate to ethanol comes at a cost, a reduction in biomass and pyru

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Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network

Abstract We report a novel computational method, RegNetDriver, to identify tumorigenic drivers using the combined effects of coding and non-coding single nucleotide variants, structural variants, and DNA methylation changes Gift Card in the DNase I hypersensitivity based regulatory network.Integration of multi-omics data from 521 prostate tumor sam

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Redescription of Crematogaster cypria Santschi, 1930, new status, with description of two new related species from Greece and Turkey (Hymenoptera, Formicidae)

Crematogaster (Crematogaster) jehovae var.cypria Santschi, 1930 is raised to species rank.Two new, related species are described from the north-eastern part of the Mediterranean Basin: Crematogaster (Crematogaster) erectepilosa sp.n.(Dodecanese, Greece) and Wheels Crematogaster (Crematogaster) gullukdagensis sp.n.(Antalya Prov., Turkey).These three

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